GOSSIP is a novel method for a global all-against-all alignment of any set of protein structures. The method detects similarities between structures down to a certain cutoff (a parameter of the program), hence allowing it to detect similar structures at a much higher speed than local structure alignment methods. GOSSIP compares many structures in times which are several orders of magnitude faster than well-known available structure alignment servers, and it is also faster than a database scanning method.
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GOSSIP: a method for fast and accurate global alignment of protein structures.
Kifer I, Nussinov R, Wolfson HJ.
Bioinformatics. 2011 Apr 1;27(7):925-32. Epub 2011 Feb 3.