GNA (Genetic Network Analyzer) is a computer tool for the qualitative modeling and simulation of genetic regulatory networks. GNA assists you in constructing a model of a genetic regulatory network using knowledge about regulatory interactions in combination with gene expression data. Moreover, it allows you to simulate the qualitative behavior of the network in response to external perturbations. The mathematical models created with GNA can be tested against observed properties of the network.
Bruno Besson, Hidde de Jong, Pedro Monteiro, and Michel Page.
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Methods Mol Biol. 2012;804:439-62. doi: 10.1007/978-1-61779-361-5_22.
Genetic network analyzer: a tool for the qualitative modeling and simulation of bacterial regulatory networks.
Batt G1, Besson B, Ciron PE, de Jong H, Dumas E, Geiselmann J, Monte R, Monteiro PT, Page M, Rechenmann F, Ropers D.
H. de Jong, J. Geiselmann, C. Hernandez, M. Page (2003),
Genetic Network Analyzer : Qualitative simulation of genetic regulatory networks,