Gk-arrays are provided as a simple-to-use C++ library dedicated to queries on large collection of sequences as produced by high-throughput sequencers (e.g. HiSeq 2000 from Illumina, 454 from Roche).Gk-arrays index k-mers of reads and allow to answer different queries on that read collection.
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Philippe N., Salson M., Lecroq T., Leonard M., Commes T., Rivals E.
Querying large read collections in main memory: a versatile data structure.
BMC Bioinformatics 2011, 12:242.