GC (Genomic Control) implements the genomic control models introduced in Devlin and Roeder (1999) and further expanded in Bacanu et al. (2002). The program runs in two steps. First, it estimates the inflation factor(s) from a set of “null” loci specified by the user. The program then uses these estimates to test for effects at either a single locus (marginal) or two loci (interaction) with relation to a user specified response variable.
- Linux / Windows
- R Package
:: MORE INFORMATION
Devlin, B., Bacanu, S., Roeder, K.,
“Genomic Control in the Extreme,”
Nature Genetics, 2004, 36(11):1129-1130.