GAMP is designed to conduct “global analysis” of DNA methylation data, particularly from the Illumina 450k Infinium platform. Instead of examining the effect of individual CpGs, the idea is to compare the overall profile or distribution of CpG measurements across individuals.
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Genet Epidemiol. 2015 Feb;39(2):53-64. doi: 10.1002/gepi.21874. Epub 2014 Dec 23.
Global analysis of methylation profiles from high resolution CpG data.
Zhao N1, Bell DA, Maity A, Staicu AM, Joubert BR, London SJ, Wu MC.