GAIN 0.2.0 / webGAIN
GAIN is based on interaction information between three attributes; in this case, between two single nucleotide polymporphisms (SNPs) and a class or phenotype attribute. Interaction information is the gain in phenotype information obtained by considering SNP A and SNP B jointly beyond the phenotype information that would be gained by considering SNPs A and B independently.
GAIN can be combined with SNPrank for a powerful analysis engine.
webGAIN is a web-based version of the Genetic Association Interaction Network (GAIN) tool
Insilico Research Group (McKinney Laboratory for Bioinformatics and In Silico Modeling)
- Linux / Windows/ MacOsX
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PLoS Genet. 2009 Mar;5(3):e1000432. doi: 10.1371/journal.pgen.1000432. Epub 2009 Mar 20.
Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis.
McKinney BA1, Crowe JE, Guo J, Tian D.