FusionSeq is a computational framework for detecting chimeric transcripts from paired-end RNA-seq experiments. It includes filters to remove spurious candidate fusions with artifacts, such as misalignment or random pairing of transcript fragments, and provides a ranked list of fusion-transcript candidates that can be further evaluated via experimental methods. FusionSeq also contains a module to identify exact sequences at breakpoint junctions.
:: MORE INFORMATION
Andrea Sboner, Lukas Habegger, Dorothee Pflueger, Stephane Terry, David Z. Chen, Joel S. Rozowsky, Ashutosh K. Tewari, Naoki Kitabayashi, Benjamin J. Moss, Mark S. Chee, Francesca Demichelis, Mark A. Rubin, Mark B. Gerstein
FusionSeq: a modular framework for finding gene fusions by analyzing Paired-End RNA-Sequencing data
Genome Biology 21 Oct. 2010; 11:R104