FusionQ is a novel fusion detection tool based on paired-end RNA-Seq data. This tool can detect gene fusions, construct the structures of chimerical transcripts, and estimate their abundances. This tool employs a new approach, “residual sequence extension”, which extends the short segments of the reads by aggregating their overlapping reads. A list of filters are proposed to control the false-positive rate.
Center for Bioinformatics & Systems Biology, The Methodist Hospital Research Institute.
- boost thread
- R Package
- Bowtie, Cufflinks
:: MORE INFORMATION
Liu C, Ma J, Chang C, Zhou X:
FusionQ: a novel approach for gene fusion detection and quantification from paired-end RNA-Seq.
BMC Bioinformatics 2013, 14:193 doi:10.1186/1471-2105-14-193