FusionHunter is a software which reliably identifies fusion transcripts from transcriptional analysis of paired-end RNA-seq. FusionHunter can accurately detect fusions that were previously confirmed by RT-PCR in a publicly available dataset. The purpose of FusionHunter is to identify potential fusions with high sensitivity and specificity and to guide further functional validation in the laboratory.
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Bioinformatics. 2011 Jun 15;27(12):1708-10. Epub 2011 May 5.
FusionHunter: identifying fusion transcripts in cancer using paired-end RNA-seq.
Li Y, Chien J, Smith DI, Ma J.