FTGI (Fast finding Three-way Gene Interactions) is a fast method for finding a three-way gene interaction,i.e. two interacting genes in expression under the genotypes of another gene, given a dataset in which expressions and genotypes are measured at once for each individual.
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Bioinformatics. 2009 Nov 1;25(21):2735-43. doi: 10.1093/bioinformatics/btp531. Epub 2009 Sep 7.
Efficiently finding genome-wide three-way gene interactions from transcript- and genotype-data.
Kayano M1, Takigawa I, Shiga M, Tsuda K, Mamitsuka H.