FLASH (Fast Length Adjustment of SHort reads) is a very accurate fast tool to merge paired-end reads from fragments that are shorter than twice the length of reads. The extended length of reads has a significant positive impact on improvement of genome assemblies.
Center for Computational Biology , Johns Hopkins University School of Medicine
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Bioinformatics. 2011 Nov 1;27(21):2957-63. Epub 2011 Sep 7.
FLASH: fast length adjustment of short reads to improve genome assemblies.
Tanja Magoč, Salzberg SL.