firestar is a server for predicting catalytic and ligand-binding residues in protein sequences.firestar makes predictions of functionally important residues using the large inventory of functionally important residues in the FireDB database. The reliability of the transfer of functional information between the functionally important residues in FireDB and the query sequence is evaluated via the local residue conservation between the two sequences.
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firestar–advances in the prediction of functionally important residues.
Lopez G, Maietta P, Rodriguez JM, Valencia A, Tress ML.
Nucleic Acids Res. 2011 Jul;39(Web Server issue):W235-41. Epub 2011 Jun 14.