Figaro is a software tool for identifying and removing the vector from raw DNA sequence data without prior knowledge of the vector sequence. By statistically modeling short oligonucleotide frequencies within a set of reads, Figaro is able to determine which DNA words are most likely associated with vector sequence.
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James Robert White, Michael Roberts, James A. Yorke and Mihai Pop
Figaro: a novel statistical method for vector sequence removal
Bioinformatics (2008) 24 (4): 462-467.