FastPval is a two stage p-value computation software which compute the empirical p-value by two stage ranking strategy, it can produce very low P-value based on huge dataset. This fast and powerful tool takes advantage of a delicate cutoff which separate the exactly significant area. Compared to the traditional ranking method, Tspvc has a good time efficiency, lower memory consuming and tiny storage spaces with high accuracy.
Bioinformatics Group, HKU Department of Biochemistry
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Mulin Jun Li, Pak Chung Sham, and Junwen Wang
FastPval: a fast and memory efficient program to calculate very low P-values from empirical distribution.
Bioinformatics. 2010 Nov 15;26(22):2897-9. Epub 2010 Sep 21.