FaSD / FaSD-somatic
FaSD is a novel SNP-detection program, to call SNPs from NGS data. Evaluated on two independent datasets from The Cancer Genome Atlas project (TCGA) with Illumina and Affymetrix SNP arrays as gold standards, FaSD showed superior performance over current state-of-the-art SNP calling softwares. FaSD is particularly accurate in calling SNPs when the sequencing depths are low, achieving area under curve (AUC) 95.2% at sequencing depths of 4-5, comparing to 86.4% for SOAPsnp and MAQ, and 73.1% for SNVmix2 on normal tissues.
FaSD-somatic is a fast and accurate somatic single-nucleotide variations (SNVs) detection program
Bioinformatics Group, HKU Department of Biochemistry
- Windows / Linux
:: MORE INFORMATION
Bioinformatics. 2014 May 14. pii: btu338. [Epub ahead of print]
FaSD-somatic: A fast and accurate somatic SNV detection algorithm for cancer genome sequencing data.
Wang W1, Wang P1, Xu F1, Luo R2, Wong MP3, Lam TW2, Wang J