ESTScan 3.03 – Detect Coding Regions in DNA/RNA Sequences

ESTScan 3.03


ESTScan is a program that can detect coding regions in DNA/RNA sequences, even if they are of low quality (e.g. EST sequences). ESTScan will also detect and correct sequencing errors that lead to frameshifts. ESTScan is not a gene prediction program , nor is it an open reading frame detector. In fact, its strength lies in the fact that it does not require an open reading frame to detect a coding region. As a result, the program may miss a few translated amino acids at either the N or the C terminus, but will detect coding regions with high selectivity and sensitivity.


ESTScan Online Version


The SIB Swiss Institute of Bioinformatics




  • Linux / Mac OS X





Lottaz C, Iseli C, Jongeneel CV, Bucher P. (2003)
Modeling sequencing errors by combining Hidden Markov models
Bioinformatics 19, ii103-ii112.

Iseli C, Jongeneel CV, Bucher P. (1999)
ESTScan: a program for detecting, evaluating, and reconstructing potential coding regions in EST sequences.
Proc Int Conf Intell Syst Mol Biol.138-48.

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.