EMSAR (Estimation by Mappability-based Segmentation And Reclustering) is a new approach for quantifying transcript abundance from RNA-seq data.The software groups reads according to the set of transcripts to which they are mapped and finds maximum likelihood estimates using a joint Poisson model for each optimal set of segments of transcripts.
Peter Park’s lab at CBMI, Harvard Medical School
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EMSAR: estimation of transcript abundance from RNA-seq data by mappability-based segmentation and reclustering.
Lee S, Seo CH, Alver BH, Lee S, Park PJ.
BMC Bioinformatics. 2015 Sep 3;16(1):278. doi: 10.1186/s12859-015-0704-z.