emmaPowerSim allows a user to perform a statistical power experiment via in silico mapping. Given a set of genotypes and related matrix between individuals (kinship matrix), emmaPowerSim estimates the threshold of association study by generating random phenotypes with a correlation structure derived from genetic background. This package also can generate the random phenotypes with a correlation structure derived from genetic background and snp effects by given user. With generated phenotype, this package computes the statistical power for in silico mapping.
- Linux / Windows / MacOsX
- R Package
:: MORE INFORMATION
Hyun Min Kang , Noah A. Zaitlen , Claire M. Wade, Andrew Kirby , David Heckerman, Mark J. Daly and Eleazar Eskin
Efficient Control of Population Structure in Model Organism Association Mapping.
Genetics. 2008 Mar;178(3):1709-23.