EMMA (Efficient Mixed-Model Association) is a statistical test for model organisms association mapping correcting for the confounding from population structure and genetic relatedness. EMMA takes advantage of the specific nature of the optimization problem in applying mixed models for association mapping, which allows us to sustantially increase the computational speed and the reliability of the results.
- Linux / Windows / MacOsX
- R Package
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Hyun Min Kang , Noah A. Zaitlen , Claire M. Wade, Andrew Kirby , David Heckerman, Mark J. Daly and Eleazar Eskin
Efficient Control of Population Structure in Model Organism Association Mapping.
Genetics. 2008 Mar;178(3):1709-23.