EH+ / EHPLUS 2.0
EHPLUS is a modified version of EH which only uses counts of genotypes that are actually observed. Each row of the data file consists of an identifying number for the genotype in question together with counts of the number of times it occurs in cases and controls. The genotype number is calculated in a similar way as for the original EH, and this number is produced automatically by PMPLUS, a program which accepts input files in the same format as PM but which outputs data in the format to be used by EHPLUS. EHPLUS also has a special method for handling memory requirement, which means that it can successfully deal with far more possible haplotypes than EH.
:: MORE INFORMATION
Zhao, Curtis, Sham (2000),
“Model-free and permutation tests for allelic associations“,
Human Heredity, 50(2):133-139.