edira 1.2.3 / ediraAMLdata 1.0.6
edira is an R package of identification of genes and gene regions for which two genetic variables display equally directed abnormalities in a collective in comparison to a reference group. Developed for use on gene expression and copy number intensities, but other genetic data is also possible.
ediraAMLdata is an R package for copy number and gene expression data from 33 AML patients with a complex aberrant karyotype, gene expression reference data from eleven healthy individuals and copy number reference data from two healthy individuals, all from the same laboratory and platform. Used as example data in the edira package.
Martin Schaefer <email@example.com>
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Bioinformatics. 2009 Dec 15;25(24):3228-35. doi: 10.1093/bioinformatics/btp592. Epub 2009 Oct 14.
Integrated analysis of copy number alterations and gene expression: a bivariate assessment of equally directed abnormalities.
Schäfer M1, Schwender H, Merk S, Haferlach C, Ickstadt K, Dugas M.