The BURST algorithm first identifies mutually exclusive groups of related genotypes in the population (typically a multilocus sequence typing [MLST] database), and attempts to identify the founding genotype (sequence type or ST) of each group. eBURST is a new software which divides an MLST data set of any size into groups of related isolates and clonal complexes, predicts the founding (ancestral) genotype of each clonal complex, and computes the bootstrap support for the assignment.
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Feil EJ, Li BC, Aanensen DM, Hanage WP, Spratt BG. 2004
eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data.
J Bacteriol. Mar;186(5):1518-30