DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism. Selected distinguishers satisfy user specified bounds on length, melting temperature and GC content, as well as redundancy and cross-hybridization constraints.
Bioinformatics Lab , Computer Science & Engineering Dept. University of Connecticut
:: MORE INFORMATION
B. DasGupta and K.M. Konwar and I.I. Mandoiu and A.A. Shvartsman,
DNA-BAR: Distinguisher Selection for DNA Barcoding,
Bioinformatics 21, pp. 3424-3426, 2005,