For accurate recognition of protein folds, a deep learning network method (DN-Fold) was developed to predict if a given query-template protein pair belongs to the same structural fold.
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Improving Protein Fold Recognition by Deep Learning Networks.
Jo T, Hou J, Eickholt J, Cheng J.
Sci Rep. 2015 Dec 4;5:17573. doi: 10.1038/srep17573.