DisGeNET is a plugin for Cytoscape to query and analyze a network representation of human gene-disease databases. For this purpose, we have developed a new gene-disease database integrating data from several public sources. DisGeNET allows user-friendly access to our database, which includes queries restricted to (i) the original data source, (ii) the association type, (iii) the disorder class of interest and (iv) specific diseases, respectively genes. It represents gene-disease associations in terms of bipartite graphs and additionally provides gene centric and disease centric views of the data. It assists the user in the interpretation and exploration of human complex diseases with respect to their genetic origin by a variety of built-in functions. Moreover, DisGeNET permits multicoloring of nodes (genes/diseases) according to their disease classes for expedient visualization
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Anna Bauer-Mehren; Michael Rautschka; Ferran Sanz; Laura I. Furlong:
DisGeNET – a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks.
Bioinformatics, Vol. 26, No. 22. (15 November 2010), pp. 2924-2926.