Aug 252015
 

DiscoTope 2.0

:: DESCRIPTION

DiscoTope predicts discontinuous B cell epitopes from protein three dimensional structures. The method utilizes calculation of surface accessibility (estimated in terms of contact numbers) and a novel epitope propensity amino acid score. The final scores are calculated by combining the propensity scores of residues in spatial proximity and the contact numbers.

::DEVELOPER

CBS (Center for Biological Sequence Analysis),  Technical University of Denmark

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

DiscoTope

:: MORE INFORMATION

Citation

Prediction of residues in discontinuous B cell epitopes using protein 3D structures
Pernille Haste Andersen, Morten Nielsen and Ole Lund
Protein Science, 15:2558-2567, 2006

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