Sep 252013
 

DISCERN

:: DESCRIPTION

Discern is a method for catalytic residue prediction derived from the combination of three ingredients: the use of the INTREPID phylogenomic method to extract conservation information; the use of 3D structure data, including features computed for residues that are proximal in the structure; and a statistical regularization procedure to prevent overfitting.

::DEVELOPER

the Berkeley Phylogenomics Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Perl
  • Python

:: DOWNLOAD

  DISCERN

:: MORE INFORMATION

Citation

Sankararaman, S., Sha, F., Kirsch, J.F., Jordan, M.I., and Sjölander, K.,
Active Site Prediction using Evolutionary and Structural Information
Bioinformatics (2010) 26 (5): 617-624.; doi: 10.1093/bioinformatics/btq008

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