Dendrix (De novo Driver Exclusivity) is an algorithm for discovery of mutated driver pathways in cancer using only mutation data. It finds sets of genes, domains, or nucleotides whose mutations exhibit both high coverage and high exclusivity in the analyzed samples.
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F. Vandin, E. Upfal, B.J. Raphael. (2011)
De novo Discovery of Mutated Driver Pathways in Cancer.
Genome Res. 2011 Jul 11