deFuse 0.8.1 – Gene Fusion Discovery using RNA-Seq Data

deFuse 0.8.1

:: DESCRIPTION

deFuse is a software package for gene fusion discovery using RNA-Seq data. The software uses clusters of discordant paired end alignments to inform a split read alignment analysis for finding fusion boundaries. A classifier trained on real fusions and false positives is applied to the assembled sequences. The software produces a fully annotated output for each predicted fusion. The software is designed to be run out of the box with little configuration, and is compatible SGE, PBS and LSF compute clusters.

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::DEVELOPER

Shah Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 deFuse

:: MORE INFORMATION

Citation

McPherson A, Hormozdiari F, Zayed A, Giuliany R, Ha G, et al. (2011)
deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data
PLoS Comput Biol 7(5): e1001138. doi:10.1371/journal.pcbi.1001138

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