deepSNV 1.32.0 – Calling Subclonal SNVs from paired Deep Sequencing Experiments

deepSNV 1.32.0

:: DESCRIPTION

deepSNV is an R package for calling subclonal single-nucleotide variants from paired deep sequencing experiments.This package provides provides a quantitative variant caller for detecting subclonal mutations in ultra-deep (>=100x coverage) sequencing experiments. It assumes a comparative setup with a control experiment of the same loci and a beta-binomial model to discriminate sequencing errors and subclonal SNVs.

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::DEVELOPER

the Computational Biology Group (CBG)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

deepSNV

:: MORE INFORMATION

Citation

Nat Commun. 2012 May 1;3:811. doi: 10.1038/ncomms1814.
Reliable detection of subclonal single-nucleotide variants in tumour cell populations.
Gerstung M1, Beisel C, Rechsteiner M, Wild P, Schraml P, Moch H, Beerenwinkel N.

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