CrossTalkZ is a statistical method and software to assess the significance of crosstalk enrichment between pairs of gene or protein groups in large biological networks.
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PLoS One. 2013;8(1):e54945. doi: 10.1371/journal.pone.0054945. Epub 2013 Jan 23.
Statistical assessment of crosstalk enrichment between gene groups in biological networks.
McCormack T, Frings O, Alexeyenko A, Sonnhammer EL.