Crossbow is a scalable, portable, and automatic Cloud Computing tool for finding SNPs from short read data. It combines Bowtie, an ultrafast and memory efficient short read aligner, and SoapSNP, and an accurate genotyper. These tools are combined in an automatic, parallel pipeline that runs in the cloud (Elastic MapReduce in this case) on a local Hadoop cluster, or on a single computer, exploiting multiple computers and CPUs wherever possible. The pipeline can analyze over 35x coverage of a human genome in one day on a 10-node local cluster, or in 3 hours for about $85 using a 40-node, 320-core cluster rented from Amazon Web Services.
:: MORE INFORMATION
Langmead B, Schatz M, Lin J, Pop M, Salzberg SL.Searching for SNPs with cloud computing.Genome Biology 10:R134.