COLOMBO is a software framework equipped with a GUI for the statistical analysis of sequences of a genome. It can be equipped with different plugins that actually perform the analysis. The current version of COLOMBO is supplied with SIGI-HMM, a tool for the prediction of Genomic Islands.
Theoretical Computer Science and Algorithmic Methods , at the University of Göttingen.
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Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models.
Waack S, Keller O, Asper R, Brodag T, Damm C, Fricke WF, Surovcik K, Meinicke P, Merkl R.
BMC Bioinformatics. 2006 Mar 16;7:142.