COILS is a program that compares a sequence to a database of known parallel two-stranded coiled-coils and derives a similarity score. By comparing this score to the distribution of scores in globular and coiled-coil proteins, the program then calculates the probability that the sequence will adopt a coiled-coil conformation.
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Lupas, A., Van Dyke, M., and Stock, J. (1991)
Predicting Coled Coils from Protein Sequences,