ChainTweak is a program for sampling the neighbourhood of a given protein backbone. It poses the problem of finding conformations which have the same bond lengths, bond angles but are within a few Angstrom (say 4A) of the original conformation. It does this by using sliding window approach to perform local modifications to the structure without modifying the distal ends.
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Pac Symp Biocomput. 2005:52-63.
Chaintweak: sampling from the neighbourhood of a protein conformation.
Singh R, Berger B.