CES simulates the evolution of a locus where the resident allele is allowed to evolve across its synonymous genotype space following the allele substitution model described in SELLA and HIRSH (2005).
:: MORE INFORMATION
Michael A. Gilchrist, Premal Shah and Russell Zaretzki
Measuring and Detecting Molecular Adaptation in Codon Usage Against Nonsense Errors During Protein Translation
Genetics December 2009 vol. 183 no. 4 1493-1505