CAT (Composition Analysis Toolkit) is a software package that includes a novel measure of codon usage bias, Codon Deviation Coefficient (CDC). Unlike previous measures, CDC effectively accounts for background nucleotide composition in estimating codon usage bias and utilizes a bootstrap assessment of the statistical significance of codon usage bias.
- WIndows/ Linux / MacOsX
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Zhang, Z., Li, J., Cui, P., Ding, F., Li, A., Townsend, J.P., and Yu, J. (2011)
Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance
BMC Bioinformatics. 2012 Mar 22;13:43.