CANGES is a systematic data integration method that links SNP and linkage disequilibrium data to pathway- and protein-protein interaction information. It can be used as a knowledge discovery tool for the search of disease associated causative variants from genome-wide studies as well as to generate new hypotheses on synergistically functioning genes.
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Karinen S, Heikkinen T, Nevanlinna H, Hautaniemi S (2011)
Data Integration Workflow for Search of Disease Driving Genes and Genetic Variants.
PLoS ONE 6(4): e18636. doi:10.1371/journal.pone.0018636