CAMBer unifies annotations of closely related species by homology transfer. It produces what we called multigene families. Each multigene family reveals genes that are in one-to-one correspondence in the bacterial strains, thereby permitting their annotations to be integrated. In our paper we present more details and results of our method applied to three human pathogens: Escherichia coli, Mycobacterium tuberculosis and Staphylococcus aureus.
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Michal Wozniak, Limsoon Wong and Jerzy Tiuryn
CAMBer: an approach to support comparative analysis of multiple bacterial strains
BMC Genomics 2011, 12(Suppl 2):S6