BRS-nonint (Balanced Random Sampling of Non-interactions) is a method of sampling non-interactions randomly from the complement graph of protein-protein interactions, while the degree of each protein in the ‘positive’ dataset (interactions) equals to that in the ‘negative’ dataset (non-interactions).
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Bioinformatics. 2010 Oct 15;26(20):2610-4. Epub 2010 Aug 27.
Simple sequence-based kernels do not predict protein-protein interactions.
Yu J, Guo M, Needham CJ, Huang Y, Cai L, Westhead DR.