BioProspector discovers conserved transcription factor binding sites among upstream sequences from co-regulated genes. BioProspector uses a Gibbs sampling approach to align and score DNA segments. It can find short (8bp), interrupted, weakly conserved (50%) and not very abundant DNA motifs from microarray data.
- windows with Cygwin / Linux / Mac OsX
- C Complier
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Liu X, Brutlag DL, Liu JS.
BioProspector: discovering conserved DNA motifs in upstream regulatory regions of co-expressed genes.
Pac Symp Biocomput. 2001;:127-38.