Apr 302015
 

BioBin 2.1.1

:: DESCRIPTION

BioBin meets a critical need for an improved binning algorithm through the advantage of prior biological knowledge and potential cumulative effects of biologically aggregated RVs. BioBin requires the Library of Knowledge Integration (LOKI), which contains diverse prior knowledge from multiple collections of biological data. BioBin can be used to apply multiple levels of burden collapsing/testing, including: regulatory regions, evolutionary conserved regions, genes, and/or pathways without a need for an external feature file. BioBin aids rare variant analysis by binning variants according to prior biological knowledge.

::DEVELOPER

Ritchie Lab

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux
  • C++ Compiler

:: DOWNLOAD

 BioBin

:: MORE INFORMATION

Citation

Pac Symp Biocomput. 2013:332-43.
Using BioBin to explore rare variant population stratification.
Moore CB, Wallace JR, Frase AT, Pendergrass SA, Ritchie MD.

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