Bhageerath 1.0 / BHAGEERATH-H
Bhageerath is an energy based computer software suite for narrowing down the search space of tertiary structures of small globular proteins. The protocol comprises eight different computational modules that form an automated pipeline. It combines physics based potentials with biophysical filters to arrive at 10 plausible candidate structures starting from sequence and secondary structure information. The methodology has been validated here on 50 small globular proteins consisting of 2-3 helices and strands with known tertiary structures. For each of these proteins, a structure within 3-6 A RMSD (root mean square deviation) of the native has been obtained in the 10 lowest energy structures.
BHAGEERATH-H is a homology ab-intio hybrid eeb server for protein tertiary structure prediction
:: MORE INFORMATION
B Jayaram, Priyanka Dhingra, Avinash Mishra, Rahul Kaushik, Goutam Mukherjee, Ankita Singh and Shashank Shekhar,
“Bhageerath-H: A homology ab initio hybrid server for predicting tertiary structures of monomeric soluble proteins“,
BMC Bioinformatics, 2014, 15(Suppl 16):S7
Bhageerath: an energy based web enabled computer software suite for limiting the search space of tertiary structures of small globular proteins.
Jayaram B, Bhushan K, Shenoy SR, Narang P, Bose S, Agrawal P, Sahu D, Pandey V.
Nucleic Acids Res. 2006;34(21):6195-204