BBSeq (Beta-Binomial modeling of the overdispersion of the RNA-seq count data)is used to identify differential expression in high-throughput count data, such as RNAseq count data which is derived from next-generation sequencing machines. Our modeling design is very flexible. It can not only solve the data with multiple comparisons, but also can find the affect from other covariates, such as age and other counfounding variables.
- R Package
:: MORE INFORMATION
Zhou YH, Xia K, Wright FA. (2011)
A Powerful and Flexible Approach to the Analysis of RNA Sequence Count Data.
Bioinformatics (2011) 27 (19): 2672-2678.