Nov 162014
 

ATHENA 1.0

:: DESCRIPTION

ATHENA (the Analysis Tool for Heritable and Environmental Network Associations) results in clear performance improvements for discovering gene-gene interactions that influence human traits. We employed an alternative tree-based crossover, backpropagation for locally fitting neural network weights, and incorporation of domain knowledge obtainable from publicly accessible biological databases for initializing the search for gene-gene interactions. We tested these modifications in silico using simulated datasets.

::DEVELOPER

Ritchie Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 ATHENA

:: MORE INFORMATION

Citation:

ATHENA: A knowledge-based hybrid backpropagation-grammatical evolution neural network algorithm for discovering epistasis among quantitative trait Loci.
Turner SD, Dudek SM, Ritchie MD.
BioData Min. 2010 Sep 27;3(1):5.

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