Asymmetry programs: AmbiguityRemover removes ambiguously aligned sites from protein sequence alignments, for input into AsymmetryCounter. AsymmetryCounter counts the number of amino acid subsitutions in each direction between pairs of protein sequences. AsymmetryScaler takes the results from AsymmetryCounter and summarizes substitutional asymmetry data in a single scale
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McDonald, J.H., A.M. Grasso, and L.K. Rejto. 1999.
Patterns of temperature adaptation in proteins from Methanococcus and Bacillus.
Mol. Biol. Evol. 16: 1785-1790.