ALOHA (Allele-Frequency/Loss-of-Heterozygosity/Allelic-Imbalance) is a tool for a genome-wide analysis of allele frequency, detection of loss of heterozygosity and identification of allelic imbalance. Moreover, chromosome-wise allele frequency biplots are provided for sample classification, outlier detection and SNP clustering.
- R Package
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Hsin-Chou Yang*, Hsin-Chi Lin, Mei-Chu Huang, Ling-Hui Li, Wen-Harn Pan, Jer-Yuarn Wu, and Yuan-Tsong Chen (2010).
A new analysis tool for individual-level allele frequency for genomic studies.
BMC Genomics 11: 415