AlignNemo (Aligning Network Modules), is a novel algorithm that, given the networks of two organisms, uncovers subnetworks of proteins that related in sequence and topology. The subnetworks have a general topology and need not to correspond to specific interaction patterns thus more closely fit the models of functional complexes proposed in the literature.
Marco Mina, Giovanni Ciriello, Pietro Guzzi.
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PLoS One. 2012;7(6):e38107. Epub 2012 Jun 12.
AlignNemo: a local network alignment method to integrate homology and topology.
Ciriello G, Mina M, Guzzi PH, Cannataro M, Guerra C.