AIRlINER is an algorithmic approach to the assessment of A-to-I (Adenosine-to-Inosine) RNA editing sites in non-repetitive regions. It determines the editing probability of an adenosine by analyzing its flanking region of 10 nucleotides. Such pattern is then combined with a similar model calculated from un-edited sequences, resulting in the estimation of an unbiased editing probability.
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Knowledge in the Investigation of A-to-I RNA Editing Signals.
Nigita G, Alaimo S, Ferro A, Giugno R, Pulvirenti A.
Front Bioeng Biotechnol. 2015 Feb 24;3:18. doi: 10.3389/fbioe.2015.00018.