AbundantOTU+ deals with sequences from rare species as well, compared to AbundantOTU!!
AbundantOTU is a software based on a Consensus Alignment (CA) algorithm,which infers consensus sequences, each representing an OTU,taking advantage of the sequence redundancy for abundant species. Pyrosequencing reads can then be recruited to the consensus sequences to give quantitative information for the corresponding species. As tested on 16S rRNA pyrosequence datasets from mock communities with known species, AbundantOTU rapidly reported identiffied sequences of the source 16S rRNAs and the abundances of the corresponding species.AbundantOTU was also applied to 16S rRNA pyrosequence datasets derived from real microbial communities and the results are in general agreement with previous studies.
:: MORE INFORMATION
Identification and quantification of abundant species from pyrosequences of 16S rRNA by consensus alignment.
The Proceedings of BIBM 2010, 153-157